YM-348 is an indazolethylamine derivative drug which acts as a potent and selective 5-HT<sub>2C</sub> receptor agonist, with an EC<sub>50</sub> of 1nM and 15x selectivity over 5-HT<sub>2A</sub>, although it only has moderate selectivity of 3x over the closely related 5-HT<sub>2B</sub> receptor. It has thermogenic and anorectic effects in animal studies, making it potentially useful for the treatment of obesity.