Xyrias guineensis is an eel in the family Ophichthidae (worm/snake eels). It was described by Jacques Blache in 1975, originally under the genus Ophisurus. It is a marine, deep water-dwelling eel which is known from Pointe Noire, Congo, in the eastern Atlantic Ocean. It is known to dwell at a depth of , and inhabits burrows formed in sand and mud sediments on the continental shelf. Males can reach a maximum total length of .