Xanthesma tuberculata, or Xanthesma (Chaetohesma) tuberculata, is a species of bee in the family Colletidae and the subfamily Euryglossinae. It is endemic to Australia. It was described in 1978 by Australian entomologist Elizabeth Exley.
The species occurs across tropical northern Australia. The type locality is 7 km east of Kununurra in the Kimberley region of Western Australia.
The adults are flying mellivores. Flowering plants visited by the bees include Eucalyptus species.