Xanthesma merredensis, or Xanthesma (Xanthesma) merredensis, is a species of bee in the family Colletidae and the subfamily Euryglossinae. It is endemic to Australia. It was described in 1974 by Australian entomologist Elizabeth Exley.
The species occurs in Western Australia. The type locality is 54 km east of Merredin. It has also been recorded from Dongara.
The adults are flying mellivores. Flowering plants visited by the bees include Eucalyptus species.