Xanthesma clethrosema , or Xanthesma (Xenohesma) clethrosema , is a species of bee in the family Colletidae and the subfamily Euryglossinae. It is endemic to Australia. It was described in 1969 by Australian entomologist Elizabeth Exley.
The species occurs in central Australia. The type locality is 22 km north of Barrow Creek in the southern part of the Northern Territory.
The adults are flying mellivores. Flowering plants visited by the bees include Eucalyptus species.