Xaa-Xaa-Pro tripeptidyl-peptidase (, prolyltripeptidyl amino peptidase, prolyl tripeptidyl peptidase, prolyltripeptidyl aminopeptidase, PTP-A, TPP) is an enzyme. It catalyses the following chemical reaction
This cell-surface-associated serine exopeptidase is found in the Gram-negative, anaerobic bacterium Porphyromonas gingivalis.