Wrightsville is an unincorporated community in Fairfield Township, Madison County, and Pleasant Township, Franklin County, Ohio, United States. The center of the community is located at , at the intersection of Ohio State Route 665 and Georgesville-Wrightsville Road, approximately north of Kiousville and just west of the county line, with some of the community extending east into Franklin County.
The Wrightsville Post Office was established on January 23, 1888, but was discontinued on January 15, 1901. The mail service is now sent through London for the Madison County portion of the community and through Grove City for the Franklin County portion.