"Without You I'm Nothing" is a 1998 single by British alternative rock band Placebo. The title track of their second album, the single version featured additional vocals by David Bowie. The single reached number 79 on the French Singles Chart, and number 52 on the Australian ARIA singles chart.
This song was also featured in an episode of the drama television series Queer as Folk and the Mexican movie Violanchelo.
The song was a staple of the band's set list from the Without You I'm Nothing tour to the Sleeping with Ghosts tour. It was also performed during the latter legs of the Meds tour. The song returned to live shows during the band's UK tour in April 2012, but was not performed during the Summer leg of the tour. It was also featured in the 2016 arena tour with accompanying visuals of Bowie working with the band to produce the track.