Willis Creek is a second-order tributary of the Cape Fear River in Cumberland County, North Carolina.
Willis Creek is formed by the junction of Swans Creek and Kirks Mill Creek near North Carolina Highway 87 northeast of St. Pauls, North Carolina. Cross Creek then flows eastward to join the Cape Fear River near the border between Cumberland County and Bladen County.
Willis Creek drains of area, receives about 48.7 in/year of precipitation, has a wetness index of 560.85 and is about 19% forested.