William Stafford-Howard, 2nd Earl of Stafford, de jure 3rd Baron Stafford ( â January 1733) was an English peer.
Stafford-Howard was born in as the son of John Stafford-Howard (d. 1714) and Mary Southcote (a daughter of Sir John Southcote). Among his siblings was Mary Stafford-Howard (wife of Francis Plowden, MP for Bannow) and John Stafford-Howard, 4th Earl of Stafford, upon whose death the earldom became extinct. After his mother's death, his father married Theresa Strickland, daughter of Robert Strickland, in . His father served as King James II's Ambassador to King Louis XIV when the former was exiled at Saint-Germain. After the King's death, his father served as vice-chamberlain to the King's widow, Queen Mary.
His paternal grandparents were William Howard, 1st Viscount Stafford, 1st Baron Stafford, and Mary Howard, Countess of Stafford (a granddaughter of the 4th Baron Stafford). His grandfather, the youngest son of Thomas Howard, 21st Earl of Arundel, was beatified as a Catholic martyr by Pope Pius XI in 1929.
On the death of his uncle, Henry Stafford-Howard, on 27 April 1719, he succeeded as the 2nd Earl of Stafford. He also succeeded as the de jure 3rd Baron Stafford.
In , he married his cousin, Anne Holman (d. 1725), daughter of George Holman and Anastasia Howard. Together, they were the parents of:
Lady Stafford died on 21 May 1725. Lord Stafford died in January 1733 and was succeeded in his titles by his only son, William.