William "Bill" Kassebaum (born February 11, 1962) is an American Republican politician.
In 2002, Kassebaum ran to serve in the sixty-eighth district of the Kansas House of Representatives, centered in Burdick, Kansas, in Morris County, Kansas. In the Republican primary on August 30, 2002, he challenged incumbent representative Shari Weber, and narrowly won, carrying 51.88 percent of the 3,851 ballots cast.
His mother is Nancy Landon Kassebaum, former United States Senator. His maternal grandfather was Alf Landon, Governor of Kansas. His brother was Richard Kassebaum, a documentary filmmaker.