William Gillespie

William or Bill Gillespie may refer to:

• William Gillespie (actor) (1894–1938), Scottish actor
• William Gillespie (New Zealand politician) (1893–1961), New Zealand politician of the National Party
• William Ernest Gillespie (1912–1967), American educator
• William John Gillespie (1897–1967), Canadian World War I flying ace
• Willie Earl Gillespie (born 1961), American football wide receiver
• Bill Gillespie (journalist) (born 1946), Canadian journalist and author
• Bill Gillespie (politician) (1928–2008), American politician
• Bill Gillespie (footballer) (1887–1927), Australian rules footballer
• Bill Gillespie (rugby league) (1894–1945), Australian rugby league player
• Billie Gillespie (1873–1942), English footballer
• Billy Gillespie (1891–1981), Irish footballer
• William David Gillespie (1934–2025), New Zealand rugby union player