William Brewster may refer to:
- William Brewster (Mayflower passenger) (1560âÂÂ1644), English official and Mayflower passenger in 1620
- William Brewster (ornithologist) (1851âÂÂ1919), American ornithologist
- William Brewster (priest) (died 1465), Canon of Windsor
- William E. Brewster (1858âÂÂ1945), American banker, merchant, and politician from Maine
- William N. Brewster (1864âÂÂ1917), American Protestant Christian missionary to China
- William R. Brewster (1828âÂÂ1869), American Civil War general
- Willie Brewster (died 1965), whose murder was the first time in the history of Alabama that a white man was convicted of killing a black man
- Bill Brewster (American politician) (1941âÂÂ2022), American politician
- Bill Brewster (Canadian politician) (1924âÂÂ2014), Canadian politician
- Bill Brewster (DJ), disc jockey and author of Last Night a DJ Saved My Life