Wilkes-Barre Academy was a private school in Wilkes-Barre, Pennsylvania, established in 1807. The school had numerous prominent alumni, including several politicians.
An old courthouse building was used before it became the Wyoming Academy, and a new brick building was constructed. Female students occupied two rooms in the school's building before the Girls' Institute was established.
In 1838, the school became Wyoming Academy.
Miner-Hillard Milling Company was a major business in the area. Many students came to the school from outside the immediate area.