Whittenburg Creek is a stream in Crawford County in the U.S. state of Missouri.
The stream headwaters are at and its confluence with the Meramec River is at . The stream source area lies between Steelville and Cherryville. The stream flows generally north passing under Route 19 south of Steelville and under Route 8 just east of Steelville. The stream flows past the historic community of Sankey and on north to join the Meramec at Birds Nest.
Whittenburg Creek has the name of a local family.