Weightlifting competitions at the 2023 Pan American Games in Santiago, Chile were held between October 21 and 24, 2023 at the Gimnasio Chimkowe in Peñalolén, a suburb of Santiago.
A total of 10 events (five each for men and women) were contested, four less than in the last edition of the games. There was a merger of the respective events: 67 kg and 73 kg for men, 109 kg and +109 kg for men, 55 kg and 59 kg for women, 87 kg and +87 kg for women.
A total of 136 weightlifters (68 per gender) qualified to compete at the games. A nation may enter a maximum of 8 weightlifters (four per gender). The host nation (Chile) automatically qualified the maximum team size. All other nations qualified through their team scores from both the 2021 and 2022 Pan American Championships combined. A further two wild cards were awarded (one per gender). Extra spots were granted to the winners of the respective categories at the 2021 Junior Pan American Games.
A total of 26 countries/teams qualified weightlifters. The number of athletes a nation has entered is in parentheses beside the name of the country or team.