Vaqiri (or Vakiri) is a village in Georgia, in the region of Kakheti, Signagi Municipality. The village lies on the northeastern foothills of the Gombori Range, approximately 9 km from Sighnaghi at an elevation of 420 m. At the 2014 census its population was 1,950, almost entirely ethnic Georgian.
In 1772, the Baltic German naturalist Johann Anton Güldenstädt, conducting fieldwork in the eastern Caucasus for the Russian Academy of Sciences, carried out research in the village.
The village contains several medieval Georgian architectural monuments. The most prominent is a three-nave basilica of John the Baptist, representing early medieval Georgian church architecture. Two further churches are dedicated to the Transfiguration, one early medieval and one dating to the 18th century. A 19th-century church and a cemetery chapel of Saint George are also present. The 17th-century Kochiaan fortress-tower stands in the village center, and the Khatiashvili house dates to 1900.
The village is home to house-museums of the Georgian writer Ilo Mosashvili and the physician Alexander Gzirishvili.