Vanesa Santana (born 3 September 1990) is an Argentine professional footballer who plays as a midfielder for CD Argual the Argentina women's national team. She has also played for the Argentina U-20 team.
Santana represented Argentina at the 2008 South American U-20 Women's Championship, 2008 FIFA U-20 Women's World Cup and the 2010 South American U-20 Women's Championship. She made her senior debut in 2011.