Valle del Guamez is a town and municipality located in the Putumayo Department, in the Republic of Colombia.
The Sinaloa Mafia is a criminal organisation that has an alliance with La Constru, a criminal groups that controls microtrafficking activities, principally of cocaine in the municipalities of Valle del Guamuez.
As of 2025, the UK Foreign, Commonwealth and Development Office advises against all but essential travel to Valle del Guamuez.