Uzbekistan competed at the 2022 World Games held in Birmingham, United States from 7 to 17 July 2022. Athletes representing Uzbekistan won one silver medal and one bronze medal. The country finished in 60th place in the medal table.
The following is the list of number of competitors in the Games.
One competitor was scheduled to represent Uzbekistan in ju-jitsu.
Uzbekistan won one bronze medal in karate.
Uzbekistan competed in muaythai.
Uzbekistan competed in rhythmic gymnastics.
Uzbekistan won one silver medal in wushu.