Uzbekistan participated at the 2018 Summer Youth Olympics in Buenos Aires, Argentina, from 6 October to 18 October 2018.
Uzbekistan qualified three boats based on its performance at the 2018 World Qualification Event.
Uzbekistan qualified a rider based on its ranking in the FEI World Jumping Challenge Rankings.
Uzbekistan qualified a mixed pair based on its performance at the 2018 Acrobatic Gymnastics World Championship.
Uzbekistan qualified two gymnasts based on its performance at the 2018 Asian Junior Championship.
Uzbekistan qualified one gymnast based on its performance at the 2018 Asian Junior Championship.
Uzbekistan qualified one gymnast based on its performance at the 2018 Asian Junior Championship.
Uzbekistan qualified one athlete based on its performance at one of the Karate Qualification Tournaments.
Uzbekistan qualified one boys' boat based on its performance at the 2017 World Junior Rowing Championships. They also qualified one girls' boat based on its performance at the 2018 Asian Youth Olympic Games Qualification Regatta.
Uzbekistan qualified three athletes based on its performance at the 2017 World Youth Championships.
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