Uzbekistan competed in the 2008 Summer Olympics held in Beijing, People's Republic of China from August 8 to August 24, 2008, with a team of 58 athletes.
<small><nowiki>*</nowiki> The athlete who finished in second place, Lyudmila Blonska of Ukraine, tested positive for a banned substance. Both the A and the B tests were positive, therefore Blonska was stripped of her silver medal, and Tarasova moved up a position.</small>
Uzbekistan qualified seven boxers for the Olympic boxing tournament. Atoev was the first to qualify, earning a spot in the light heavyweight class at the 2007 World Championships. Four more boxers (both Sultonovs, Mahmudov, and Rasulov) qualified at the first Asian qualifying tournament. Doniyorov and Tadjibayev both qualified at the second qualifier.
<small>Qualification Legend: QS = Qualify to semi-final; QF = Qualify directly to final</small>
<small>Qualification Legend: FA=Final A (medal); FB=Final B (non-medal); FC=Final C (non-medal); FD=Final D (non-medal); FE=Final E (non-medal); FF=Final F (non-medal); SA/B=Semifinals A/B; SC/D=Semifinals C/D; SE/F=Semifinals E/F; QF=Quarterfinals; R=Repechage</small>
Qualifiers for the latter rounds (Q) of all events were decided on a time only basis, therefore positions shown are overall results versus competitors in all heats.