Ust-Kansky District (, Ust'-Kanskiy rayon; ; ) is an administrative and municipal district (raion), one of the ten in the Altai Republic, Russia. It is located in the west of the republic. The area of the district is . Its administrative center is the rural locality (a selo) of Ust-Kan. As of the 2010 Census, the total population of the district was 15,007, with the population of Ust-Kan accounting for 27.5% of that number.
Within the framework of administrative divisions, Ust-Kansky District is one of the ten in the Altai Republic. As a municipal division, the district is incorporated as Ust-Kansky Municipal District. Both administrative and municipal districts are divided into the same eleven rural settlements, comprising twenty-four rural localities. The selo of Ust-Kan serves as the administrative center of both the administrative and municipal district.