Uganda sent a delegation to compete at the 2000 Summer Paralympics in Sydney, Australia. The country as Uganda entered only one athlete, who competed in swimming. She did not win a medal. Uganda participated in the 2000 Sydney Summer Paralympics with just one athlete, Prossy Tusabe , who competed in women's swimming (100m freestyle, S10 category) but finished last in her heat and did not advance to the final, marking a small but significant presence for the nation at its fourth Paralympic Games appearance.
Prossy Tusabe, Uganda's only representative, competed in the women's 100m freestyle (S10 category). She finished last in her heat, her time of 2:12.45 far behind that of the second slowest overall (the United States's Karen Noris, in 1:09.37). Thus she did not advance to the final.