Histone demethylase UTY, or Ubiquitously transcribed tetratricopeptide repeat, Y chromosome, is an enzyme that in humans is encoded by the UTY gene.
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in proteinâÂÂprotein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. Alternative splicing results in multiple transcript variants encoding different isoforms.
The X-chromosome version of this gene is called UTX.
UTY has been shown to interact with TLE1 and WDR90.