USS San Diego (LPD-22), a , is the fourth ship of the United States Navy to be named for San Diego, California.
Secretary of the Navy Gordon R. England named the San Diego on 30 April 2004:
The city is the home of Naval Base San Diego, the Navy's largest base in the Pacific, and Marine Corps Recruit Depot San Diego, the United States Marine Corps' west coast recruit training center.
San Diego keel was laid down on 23 May 2007, at Northrop Grumman's Ingalls shipyard in Pascagoula, Mississippi. She was launched on 7 May 2010, and christened on 12 June, sponsored by Linda Winter, wife of former Navy secretary Donald C. Winter.
On 1 October 2011, it was announced that San Diego had completed her builders trials, including tests of her defensive, communications, propulsion, and other auxiliary systems, leaving only the repair of issues that arose in the builders trials and thereafter Navy Acceptance Trials before delivery. Her acceptance trials were completed on 17 November, ahead of her delivery to the Navy on 19 December.
San Diego departed Pascagoula on 15 March 2012 and arrived at Naval Station Guantanamo Bay, Cuba, on 19 March for a three-day layover on her way to San Diego. San Diego passed through the Panama Canal on 25 March. She arrived in San Diego on 6 April. San Diego was commissioned on 19 May 2012, in a ceremony at the Navy Pier (next to the USS Midway Museum) in San Diego.
In late 2014, San Diego operated with the Amphibious ready group in the United States Fifth Fleet area.
In March 2026, The Wall Street Journal reported that had been deployed, and was en route, to the Middle East to provide support for Operation Epic Fury. Tripoli is part of an amphibious ready group (ARG), and is being accompanied by San Diego and . The ARG is reportedly transporting around 2,200 Marine Corps personnel from the Okinawa-based 31st Marine Expeditionary Unit (MEU) and will join the -led Carrier Strike Group 3 which is already deployed in the region.
San Diego and New Orleans crossed the strait one day prior to Tripoli which was approaching the northern exit of the Strait of Malacca on 17 March 2026 as per the AIS tracking data accessed by the CNN. As of 20 March, the ships are located to the south of Sri Lanka and is expected to enter the Arabian Sea the following week and will reach the war theatre around 22âÂÂ23 March.
Meanwhile, the president of the United States has explained in a press conference that he is not "putting troops anywhere" though he would not tell the journalists even if he had taken such decision. However, Reuters cited multiple US security officials saying that the Trump administration is still "considering deploying thousands of U.S. troops to reinforce its operation in the Middle East". The ARG deployment might also be used to free or open the Strait of Hormuz or assaulting the Kharg Island. There has been no firm decision.
On 19 March 2026, Newsmax reported that might join the Tripoli Amphibious Ready Group since San Diego, which initially sailed with Tripoli and New Orleans, is expected to "hang back" to the Pacific for maintenance which was in the Philippine Sea. On the other hand, the US military also accelerated the deployment of the Boxer Amphibious Ready Group from San Diego.
On 17 July 2020, The San Diego Union-Tribune reported that sailors of San Diego had stated, on condition of anonymity, that at least five sailors from their ship had tested positive for COVID-19 during the preceding few days. The sailors had been interviewed by the Union-Tribune presumably regarding a fire aboard nearby amphibious assault ship . In response, a Navy spokesperson confirmed that two sailors who were part of the firefighting effort had tested positive for the virus.
The two sailors had shown symptoms of the disease. One was part of a crew fighting the fire, and the other had been acting as support. One sailor who fought in the fire stated that the fire had destroyed much of Bonhomme Richards firefighting gear, so the gear of nearby ships, including that of San Diego, was being used, and sailors fighting the fire often swapped gear with each other. In addition, 27 close contacts had been identified and placed in quarantine.