USS Nautilus may refer to:
- , a 12-gun schooner (1799âÂÂ1812)
- , a 76-foot coast survey schooner (1838âÂÂ1859)
- , a Narwhal-class submarine (1930âÂÂ1945)
- , the first nuclear submarine (1954âÂÂ1980)
See also
- Ships named Nautilus
- , a H-class submarine (1913âÂÂ1930) called Nautilus only during construction
- , a 66-foot patrol/escort (1917âÂÂ1919)
- , an O-11-class submarine (1917âÂÂ1931) which carried the name Nautilus during a civilian arctic expedition in 1931
- Nautilus, a cephalopod which is the namesake of these vessels