USS Lexington may refer to these ships of the United States Navy:
- , a brigantine acquired in 1776 and captured in 1777
- , a sloop-of-war in commission from 1826âÂÂ1830 and 1831âÂÂ1855
- , a timber-clad gunboat in commission from 1861âÂÂ1865
- , later USS SP-705, a patrol vessel in commission from 1917âÂÂ1918
- , a , converted to CV-2 in 1922
- , a commissioned in 1927 and sunk in 1942
- , an in commission from 1943âÂÂ1991, now a museum in Corpus Christi, Texas