USRC James Guthrie was a revenue cutter used as a harbor vessel at Baltimore, Maryland. Originally the merchant tug George W. Loane she was purchased in 1868 for 16,500 and was named for James Guthrie, twenty first Secretary of the Treasury. Her duties were customs inspections and vessel movement in Baltimore harbor. She was reported unfit for service in 1881, repaired, decommissioned and sold 3 April 1882 to M.J. Ash for 4030.95.