UFC Fight Night: Edwards vs. Brady (also known as UFC Fight Night 255 and UFC on ESPN+ 113) was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on March 22, 2025, at The O<sub>2</sub> Arena in London, England.
The event marked the promotion's 16th visit to London and first since in July 2023.
A welterweight bout between former UFC Welterweight Champion Leon Edwards and Jack Della Maddalena was originally scheduled to headline the event. However, Della Maddalena was pulled from the contest in order to face current welterweight champion Belal Muhammad at UFC 315 and was replaced by Sean Brady.
A light heavyweight bout between Alonzo Menifield and Oumar Sy was scheduled for this event. However, Sy withdrew from the fight due to an injury, so Menifield was moved to in February against promotional newcomer Julius Walker.
A women's strawweight bout between Molly McCann and Istela Nunes was scheduled for this event. However, Nunes withdrew from the fight for unknown reasons and was replaced by promotional newcomer Alexia Thainara.
The following fighters received $50,000 bonuses.