UB-165 is a drug which acts as an agonist at neuronal nicotinic acetylcholine receptors being a full agonist of the ñ3ò2 isoform and a partial agonist of the ñ4ò2* isoform. It is used to study the role of this receptor subtype in the release of dopamine and noradrenaline in the brain, and has also been used as a lead compound to derive a number of other selective nicotinic receptor ligands.