U.S. Route 89 (US 89) is a part of the U.S. Highway System that travels Flagstaff, Arizona, north to the Canadian border; broken into two segments by Yellowstone National Park where unnumbered park roads serve as a connector. In the state of Wyoming, it extends approximately from the Idaho state line near Geneva, Idaho to the southern entrance of Yellowstone National Park. US 89 passes through many scenic sites including Grand Teton National Park, the Jackson Hole valley, the Snake River Canyon, and Star Valley and is the backbone visitor highway for two U.S. National Parks.
US 89 enters Wyoming in Lincoln County from Idaho and crosses Salt River Pass before passing through the Star Valley. At Alpine US 89 concludes a section where it is independent of another U.S. highway, the only such section in Wyoming. It begins its concurrency with US 26 and travels northeastward through the Snake River Canyon, crossing into Teton County. At Hoback Junction, the routes meet US 189, US 191 and the Wyoming Centennial Scenic Byway. The four routes cosigned for , entering the Jackson Hole valley where US 189 terminates in Jackson.
North of Jackson, US 26, US 89, and US 191 enter Grand Teton National Park and continue their concurrency for to Moran; at Glacier View Turnout a view of Teton Glacier, on the north of Grand Teton, can be seen. At Moran, the routes meet US 287 where US 26, US 287 south, and the Wyoming Centennial Scenic Byway head east towards Dubois. US 89 and US 191 become concurrent with US 287 and the three routes pass unsigned through the Moran Entrance Station and along side Jackson Lake. Leaving Grand Teton National Park, the three routes travel through John D. Rockefeller Jr. Memorial Parkway before reaching the South Entrance of Yellowstone National Park. Officially US 89 and other U.S. Routes are officially discontinuous through the park, though some commercially produced maps show these highways running inside Yellowstone National Park itself along its unnumbered roads. US 89 resumes at the North Entrance at Gardiner, Montana.