was the 3rd daimyà  of Hirosaki Domain in northern Mutsu Province, Honshà «, Japan (modern-day Aomori Prefecture). His courtesy title was Tosa-no-kami, and his Court rank was Junior Fifth Rank, Lower Grade.
Tsugaru Nobuyoshi was the eldest son of Tsugaru Nobuhira, 2nd daimyà  of Hirosaki Domain, and was born at the domainâÂÂs exclave located in Kà Âzuke Province. His mother, Tatsu-hime, was the daughter of Ishida Mitsunari and had been demoted to the status of concubine and exiled to Kà Âzuke when Nobuhira married Tokugawa IeyasuâÂÂs niece to secure his position vis-à-vis the Tokugawa shogunate. He was brought to the domain(s Edo residence in 1623, on the death of his mother. He was still 13 years old when his father died, and was ordered to report before shà Âgun Tokugawa Iemitsu together with his younger half-brother Tsugaru Nobufusa on his accession to the lordship.
However, his position as the son of a concubine resulted in a split in the ranks of the senior retainers of Tsugaru Domain, with a large faction supporting Tsugaru Nobufusa due to his blood connection to the Tokugawa, and due to the fact that he was born as son of NobuhiraâÂÂs official wife. This resulted in an O-Ie Sà Âdà  known as the Funahashi Sà Âdà  of 1634, which was only suppressed with the assistance of the Tokugawa shogunate and which resulted in the exile of a number of NobufusaâÂÂs supporters in 1636. Problems arose again in 1647 in what was called the Shà Âhà  Sà Âdà Â, with remaining supporters of Nobufusa demanding that Nobuyoshi retire in favour of his younger half-brother, alleging misgovernment through excessive drinking and womanizing.
Nobuyoshi did have 25 sons and 26 daughters through a large number of concubines. However, he also continued his fatherâÂÂs works in increasing the production in his domain by developing new paddy fields, irrigation, and by developing copper and silver mines. He was also known as a waka poet.
Nobuyoshi died on December 22, 1655, at the clan residence in Kanda, Edo, at the age of 37. His grave is at the temple of Myà Âju-ji in Setagaya-ku, Tokyo, and also the Tsugaru clan temples of Chà Âshà Â-ji and Hà Âon-ji in Hirosaki. Four of his senior retainers decided to follow him in death by committing Junshi .
Nobuhira was succeeded by his eldest son, Tsugaru Nobumasa.