In Toxoplasma gondii the translational repression of lactate dehydrogenase 1 (LDH1) was discovered to be mediated through its 5â²UTR. A small nucleotide regulatory RNA hairpin was shown to be essential for the repression. It is possible that this hairpin may act as the nucleation site for the binding of a trans-acting factor(s) that allow for the translational repression.