Towthorpe is a hamlet and former civil parish, now in the parish of Fimber, in the East Riding of Yorkshire, England. It is situated in the Yorkshire Wolds just north of the B1248 road, approximately north-west of Driffield and south-west of Sledmere. In 1931 the parish had a population of 66. The deserted medieval village is a scheduled monument. The name Towthorpe derives from the Old Norse Toveþorp or Tofiþorp, meaning 'Tove/Tofi's secondary settlement'.
Towthorpe was formerly a township in the parish of Wharram Percy, in 1866 Towthorpe became a civil parish, on 1 April 1935 the parish was abolished and merged with Fimber.