Tony Pignatiello (born 29 April 1968) is a retired Canadian soccer player who played at both professional and international levels as a midfielder.
Pignatiello played club football for Toronto Italia, York Lions, North York Rockets, Toronto Blizzard and Nova Scotia Clippers. Pignatiello represented Canada at the 1987 Pan American Games and at the 1987 FIFA World Youth Championship.
Pignatiello earned twelve caps for the Canadian national side in 1988, scoring one goal.