Tombusvirus 3â² UTR is an important cis-regulatory region of the Tombus virus genome.
Tomato bushy stunt virus is the prototype member of the family Tombusviridae. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate. In addition to viral proteins p33 and the RNA-dependent RNA polymerase p92, and unknown host factors, conserved and structural regions within the 3â² untranslated region (3â² UTR) are important for regulating genome replication. This 3â² structural element contains a pseudoknot.
Other non-coding RNA structures in Tombusvirus include the 5â² UTR and an internal replication element.