Thomas Nelson House is a historic home located at Peekskill, Westchester County, New York. It was built about 1860 and is a two-story, frame dwelling with a slightly hipped roof in the Italianate style. It has a two-story rear wing. It is clad in clapboard and sits on a stone and brick foundation. It features a one-story, open front porch with scrolled brackets, paired posts, and bracketed eaves. Also on the property is a contributing well house.
It was added to the National Register of Historic Places in 2001.