Tha Maka (, ) is the southeasternmost district (amphoe) of Kanchanaburi province, central Thailand and is located west of Bangkok.
Neighbouring districts are (from the west clockwise) Tha Muang, Phanom Thuan of Kanchanaburi Province, Song Phi Nong of Suphanburi province, Kamphaeng San of Nakhon Pathom province, and Ban Pong of Ratchaburi province.
The important water resource is the Mae Klong River.
The district is divided into seventeen subdistricts (tambons), which are further subdivided into 154 administrative villages (mubans).
As of December 2024 there are: nine municipal (thesaban) areas in the district: Tha Ruea Phra Thaen () is a town municipality (thesaban mueang) and covers parts of Tha Ruea and Takhram En subdistricts. Further there are eight subdistrict municipalities (thesaban tambons) of which Nong Lan and Tha Mai both cover the whole subdistrict; Phra Thaen and Phra Thaen Lam Phraya cover the entire Phra Thaen subdistrict; Don Khamin, Wai Niao and Tha Maka cover parts of the same named subdistrict.
The non-municipal areas are administered by twelve subdistrict administrative organizations - SAO (ongkan borihan suan tambon - o bo toh).
Tha Maka district is served by two hospitals
In the district there are fifteen health-promoting hospitals in total; except for Tha Maka and Tha Ruea, all subdistricts have a health promoting hospital.
There are forty-six Theravada Buddhist temples in the district.
The Christians have six churches and muslims have one mosque.