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Tenilapine

Tenilapine is an atypical antipsychotic which has never been marketed in the US.

Pharmacodynamics

Tenilapine has a relatively high affinity for the 5-HT<sub>2A</sub> receptor, and relatively low (micromolar) affinities for dopamine receptors.

The ratio of D<sub>2</sub> to D<sub>4</sub> bonding is similar to that of clozapine. Like many other atypical antipsychotics, it is a potent 5-HT<sub>2C</sub> antagonist.

References