Take Two with Phineas and Ferb is a live-action/animated hybrid short-form talk show series that premiered on Disney Channel on December 3, 2010. It is a spin-off of the animated series Phineas and Ferb and revolves around the two animated characters Phineas and Ferb interviewing live-action celebrities, a premise which bears similarities to that of the late-night animated talk show Space Ghost Coast to Coast on Adult Swim. Several other local guests have appeared in countries outside the United States.
The series aired from December 3, 2010 until November 25, 2011. The first ten episodes of the series were later released on the streaming service Disney+.
Many other local guests have appeared in countries outside the United States.