The Taipei Economic and Cultural Office in Brazil () (Portuguese: Escritório Econômico e Cultural de Taipei no Brasil) represents the interests of Taiwan in Brazil in the absence of formal diplomatic relations, functioning as a de facto embassy. Its counterpart in Taiwan is the Commercial Office of Brazil to Taipei in Taipei.
There is also a Taipei Economic and Cultural Office in São Paulo, Brazil's largest city. This was formerly known as the Centro Comercial de Taipei no Brasil. The Office is headed by a Representative, Isaac Tsai.