Khwaja Syed Mohammad Nizami (died 7 February 2026) was an Indian Muslim scholar who was the chief sajjadanasheen (head custodian) of Nizamuddin Aulia Dargah Shrine. He was the nephew of and was his successor to Dargah Shrine from 2015.
After the death of his father, Mahdi Nizami, when Khwaja Syed Mohammad Nizami was around 18, he was guided towards Islamic mysticism by his uncle, Khwaja Hasan Sani Nizami. He had held the post of the head custodian of the dargah since 2015.
Known for his commitment to Sufism and love for Hindustani classical music, Nizami was widely respected by followers and disciples from around the world.
He wanted to carry the family's legacy of music and literature forward. He was the grandson of Khwaja Hasan Nizami, a Sufi saint and Urdu essayist, wrote extensively on the Indian freedom struggle.
Nizami died on 7 February 2026 from suffocation in a house fire caused by an exploding electric water heater at his residence. He was succeeded by his two sons, Syed Shafi Nizami and Syed Hasan Nizami.
His death was mourned by different prominent leaders and politicians of India and was seen as a major loss to the global Sufi community and the Hindustan's Ganga Jamunee Tahzeeb.