Sydenham railway station is located in the townland of Ballymisert in east Belfast, and is within walking distance of Belfast City Airport and Victoria Park. The station is unstaffed, and was opened on 1 November 1851.
Mondays to Saturdays there is a half-hourly westbound service towards Belfast Grand Central in one direction, and a half-hourly eastbound service towards and Bangor in the other, with extra services at peak times.
In the evenings, the service reduces to hourly operation. Some peak-time express trains will pass through this station without stopping.
On Sundays there is an hourly service in each direction.