Stotts Run is a long 2nd order tributary to Buffalo Creek in Brooke County, West Virginia. This is the only stream of this name in the United States.
According to the Geographic Names Information System, it has also been known historically as:
Stotts Run rises about 1.5 miles north of West Liberty, West Virginia, and then flows east and northeast to join Buffalo Creek about 1 mile west of Bethany.
Stotts Run drains of area, receives about 40.3 in/year of precipitation, has a wetness index of 288.24, and is about 72% forested.