Sterling Creek is a river located in Herkimer County in the U.S. State of New York. It flows into the Mohawk River east-southeast of the Hamlet of West Schuyler.
Aquatic life, recreation uses, and natural resources habitat are stressed in Sterling Creek due to habitat modifications and resulting silt and sediment deposits in the stream. A macroinvertebrate assessment of Sterling Creek near the mouth was conducted in 2000, which showed slightly impacted conditions.