St. James's Church is an Anglican church in the evangelical tradition in the town of Glossop, Derbyshire, in the north-west of England. Along with St. Luke's Church, it makes up Whitfield Parish within Derby Diocese.
The churchyard contains war graves of three soldiers of World War I, and a Grade II listed memorial to Samuel Wood, a local mill-owner.
The foundation stone was laid on 27 September 1844 and construction started to the designs of the architect Edwin Hugh Shellard. The church was consecrated on 8 September 1846 by the Bishop of Lichfield. The chancel was enlarged in 1897 by Naylor and Sale, and a vestry added at the turn of the 20th century. In 2000, the church was designated a Grade II listed building.
The church has a pipe organ by Forster and Andrews dating from 1859. A specification of the organ can be found on the National Pipe Organ Register.