St. Mary's South is a parliamentary constituency in the parish of Saint Mary, Antigua and Barbuda. A by-election was held in the constituency on 24 October 2023.
St. Mary's South has three polling districts; "A", "B", and "C". Polling District "A" includes Jolly Hill, Bolans, Christian Valley, Willocks, Roses, Orange Valley, Picarts, Ffryes, and Valley Church. Polling District "B" includes Crabs Hill and Johnsons Point. Polling District "C" includes Urlings, Cades Bay, and Brooks.