St. Johnston (or St. Johnston Village) is a settlement in the northwest of the island of Antigua. It lies to the east of the capital, St. John's, of which is virtually a suburb. Potters Village lies immediately to the southeast. It was named for the Governor General of the Leeward Islands, Sir Thomas Reginald St. Johnston who built a hospital there.
St. Johnston has two enumeration districts. It is considered a part of St. John's City.