St. James's Church, Wuhu () is a Protestant church located in Jinghu District, Wuhu, Anhui, China.
St. James's Church's history stretches back to 1905, founded by the Episcopal Church.
In June 2011, the church was moved eastward. The church was inscribed as a municipal cultural relic preservation organ in October 2001 and a provincial cultural relic preservation organ in December 2012, respectively.
The church has a width of , a depth of and a construction area of . The bell tower is high and adopts Gothic architectural style.